The U.S. squad, which is 4-0, faces Panama on Wednesday in the final preliminary game before the second round.
Archer, named the Cubs' Minor League Pitcher of the Year for 2010, gave up three runs on four hits and struck out five over four innings. He did give up a home run to Tony Batista in the fourth and did not get a decision.
Colon, who won the American League Cy Young award in 2005, served up six earned runs in 2 1/3 innings, giving up seven hits and one walk.
Outfielder Brett Jackson, the Cubs' No. 1 Draft pick in 2009, did not play. He came out of Monday's game as a precautionary measure because of a sore heel. Jackson is batting .667 in the tournament, including a three-run homer in the opening game.
Carrie Muskat is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.