Wood, who is trying to comeback from shoulder problems, had thrown four innings for the Mesa Rookie League team before beginning his rehab stint this week in Peoria.
Wood, who pitched Tuesday, threw 12 pitches on Thursday and faced four batters. He came on in relief of Jacob Renshaw in the seventh inning, and got the first batter, Dayton's Logan Parker, to fly out to left. Wood then struck out Carson Kainer swinging, and Eddy Rodriguez singled to center. Rodriguez advanced on a wild pitch by Wood, who then struck out Zachary Cozart.
Wood's fastball ranged from 93-94 mph. He was scheduled to throw Friday, and Cubs general manager Jim Hendry will be there to watch. It'll be the first time the right-hander has pitched back-to-back outings.
"It's the first real step toward where we're really at in terms of a time frame," said Hendry, who was with the big league team Thursday. "Woody has been through this enough to temper the enthusiasm on how it's going.
"Once you go back to back and feel good the next day, then you can re-adjust and look at it a little differently as far as what it will take to get back here," Hendry said. "The day after will be as important or more important than what happens [Friday] night."
The Cubs aren't expected to announce the next phase of Wood's rehab until they see how he feels on Saturday.
"When he comes back, you want him to be able to do the work load," Hendry said. "It's a great story, and he certainly would be a big boost for the ballclub. He knows you have to blend right in and do the work. It's not one day and then a couple days off."
Carrie Muskat is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.