"[Wednesday] evening is when a lot of people hone in on the deals they want to make," he said.
The Cubs made their blockbuster move on July 4, trading starters Jeff Samardzija and Jason Hammel to the Athletics for four players, including highly touted shortstop Addison Russell and outfielder Billy McKinney.
Other teams are still trying to find the right match.
"People try to find a dance partner on the 30th and 31st," Hoyer said. "As you get to [Wednesday] evening, people want to make deals, and they're more willing to pair up, and I expect that to be the same thing."
Manager Rick Renteria does not feel that his players are thinking too much about the deadline.
"There are things they can't control," Renteria said. "I don't sense they're too preoccupied with it now."
Carrie Muskat is a reporter for MLB.com. She writes a blog, Muskat Ramblings, and you can follow her on Twitter @CarrieMuskat. This story was not subject to the approval of Major League Baseball or its clubs.