"We might keep doing what we were doing before when we had [Chris] Coghlan leading off and Mendy second," Renteria said Saturday. "We might do that to give Mendy a different look. We'll keep mixing and matching throughout the season."
Alcantara led off at Triple-A Iowa and is used to the role. But this is the big leagues.
"We've put him in a situation at the Major League level to lead off, and it's not an easy thing to do," Renteria said. "He's holding his own and battling in his at-bats. I think by putting him in the two-hole every now and then it'll give him a chance to take a breath and step back rather than try to grind out that first at-bat of the ballgame."
Bonifacio batted first in 63 games while with the Cubs before he was traded to the Braves on Thursday.
Carrie Muskat is a reporter for MLB.com. She writes a blog, Muskat Ramblings, and you can follow her on Twitter @CarrieMuskat. This story was not subject to the approval of Major League Baseball or its clubs.