Rizzo went 1-for-4 with a home run, his 30th of the season. He is the seventh left-handed batter in Cubs history to hit at least 30 homers in a season. The last to do so was Fred McGriff, who hit 30 in 2002.
"It's great, especially in this organization with a lot of history, a lot of great players," he said of his homer. "But the season's not over, you've just gotta keep going and keep playing."
Chris Valaika replaced Rizzo at first base.
Carrie Muskat is a reporter for MLB.com. She writes a blog, Muskat Ramblings, and you can follow her on Twitter @CarrieMuskat. Manny Randhawa is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.